Intestinal Transport of Amino Acid Residues of Dipeptides
نویسندگان
چکیده
منابع مشابه
Intestinal Transport of Dipeptides
A 30 cm segment of the duodenum, jejunum, or ileum of normal human volunteers was perfused, on separate occasions, with test solutions containing either glycylglycine, free glycine, glycylleucine, or equimolar amounts of free glycine and free leucine. Luminal fluid contained no hydrolytic activity against glycylglycine and minimal activity against glycylleucine. In each intestinal segment, amin...
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There are obvious analogies between disorders of intestinal amino-acid absorption and the more familiar anomalies of carbohydrate absorption. Both monosaccharides and free amino acids are important water-soluble nutrients which must be transported across the lipid-containing intestinal cell membrane by specific active transport processes involving concentration of the compounds within the cell ...
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The flux of the glycine residue of glycyl-L-proline (GlyPro) from intestinal lumen into mucosal cell was investigated in rabbit ileum. Measurements of tissue W, after 60-s exposure of the mucosal surface to [Gly-W]Gly-Pro at concentrations from 0.05 to 32 m, suggest two saturable influx processes, one with a V,,, of 0.59 pmole per cm2 hr and an apparent affinity constant (K,) of 0.93 II~M, and ...
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CHRISTENSEN, HALVOR N., BRUCE H. FELDMAN, AND A. BAIRD HASTINGS. Concentrative and reversible character of intestinal amino acid transport. Am. J. Physiol. 205(2): 255-260. Ig63.Either a-aminoisobutyric acidI -Cl4 or I -aminocyclopentanecarboxylic acid-I-Cl4 was injected into a rat and, after at least 24 hr, a suitable dilution of the same solution of the amino acid was introduced into an intes...
متن کاملPolarizabilities of amino acid residues
Over the last couple of years, it has been shown that Time Dependent Density Functional Theory (TD-DFT) is able to predict accurately and efficiently the polarizability of molecules, when using appropriate exchange-correlation potentials and (large) basis sets. In a previous paper, we compared the accuracy of the predicted mean polarizabilities of 15 organic molecules with experiment, and with ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1971
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)62163-5